The Moon would just appear a bit larger in the sky. How many larger?
Since the size correlates with the square of the distance and the area of the circle correlates to the square of the size (it is a sphere, but that is projected as a circle in our retinas), this means that:
$$ \text{actual size} = \frac{(2,159.2\text{ miles})^2}{(238,900\text{ miles})^2} = \frac{4,662,144.64\text{ miles}^2}{57,073,210,000\text{ miles}^2} = 0.0000816...$$
$$ \text{proposed size} = \frac{(2,500\text{ miles})^2}{(200,000\text{ miles})^2} = \frac{6,250,000\text{ miles}^2}{40,000,000,000\text{ miles}^2} = 0.00015625$$
$$ \text{elargement factor} = \frac{\text{proposed size}}{\text{actual size}} = \frac{0.00015625}{0,0000816...} = 1.9148...$$
I.E, The Moon would be seen on the sky almost with the double of the size in area (191.48% to be precise), which is roughly 38% larger in diameter (the square root of 1.9148 is 1.38377).
Let's suppose that our larger Moon has the same density as our common Moon. By which factor the Moon mass get larger?
Mass would be measured by $m = v \times d$, where $m$ is mass, $v$ is volume and $d$ is density. The volume of a sphere is $v = \frac{4}{3} \pi r^3$. So, we have that $m = \frac{4}{3} d \pi r^3$:
$$\text{Actual Moon mass} = \frac{4}{3} \pi (\frac{2159.2}{2})^3 d = \frac{(2159.2)^3 \pi d}{6} = 10,066,502,706.688 \frac{\pi d}{6}$$
$$\text{Proposed Moon mass} = \frac{4}{3} \pi (\frac{2500}{2})^3 d = \frac{(2500)^3 \pi d}{6} = 15,625,000,000 \frac{\pi d}{6}$$
$$\text{Mass elergement factor} = \frac{\text{proposed mass}}{\text{actual mass}} = \frac{15,625,000,000 \frac{\pi d}{6}}{10,066,502,706.688 \frac{\pi d}{6}} = 1,5521...$$
This means that the proposed Moon is 55% more massive than our actual one.
Now lets measure gravity attraction as $\text{gravity} = \frac{\text{mass}}{\text{distance}^2}$:
$$\text{Actual Moon gravity} = \frac{10,066,502,706.688 \frac{\pi d}{6}}{(238,900 \text{ miles})^2} =$$
$$= \frac{10,066,502,706.688 \frac{\pi d}{6}}{57,073,210,000\text{ miles}^2} = 0.17637... \frac{\pi d}{6} \text{miles}^{-2}$$
$$\text{}$$
$$\text{Proposed Moon gravity} = \frac{15,625,000,000 \frac{\pi d}{6}}{(200,000 \text{ miles})^2} =$$
$$= \frac{15,625,000,000 \frac{\pi d}{6}}{40,000,000,000\text{ miles}^2} = 0.390625 \frac{\pi d}{6} \text{miles}^{-2}$$
$$\text{}$$
$$\text{Gravity elergement factor} = \frac{\text{proposed gravity}}{\text{actual gravity}} = \frac{0.390625 \frac{\pi d}{6} \text{miles}^{-2}}{0.17637... \frac{\pi d}{6} \text{miles}^{-2}} = 2.21469...$$
This would also means that the gravity that the Moon would exerce onto Earth would have 221.46% of the strength, which means tides with a bit more than the double of the strength. Assuming that the proposed Moon has the same density than our actual Moon.
About the Earth's axial tilt. By searching in wikipedia:
Lunisolar precession is caused by the gravitational forces of the Moon and Sun on Earth's equatorial bulge, causing Earth's axis to move with respect to inertial space. Planetary precession (an advance) is due to the small angle between the gravitational force of the other planets on Earth and its orbital plane (the ecliptic), causing the plane of the ecliptic to shift slightly relative to inertial space. Lunisolar precession is about 500 times greater than planetary precession.
This would translate in a precession of equinoces where the lunisolar component would be significantly larger.
Otherwise, the changes in Earth are not very significative. Things would be probably much as they are like today.