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Boundary conditions: 1) You need centuries for the mutation to spread. Assuming that population is stable (actually not so problematic assumption, because the calculation would remain the same, if both populations were growing with identical speed) 20 years per generation, 2 surviving sons => 2^5 per century. So just from mutation to producing a million of ...


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As the top answer in the linked question indicates, this sort of mutation is a very serious problem for humanity which fortunately can be quite easily mitigated with modern national- and international-level identification and amelioration programs. So it is essential that your story begins prior to the discovery of modern genetics at the beginning of the ...


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Specific Person: Genghis Khan. It's late enough in humanity development to have continents not affected by it but his impact on child bearing is noticeable. Not to mention that people think that after wars there should be increase in boys being born (they also think increased boys being born means war but whatever). A place in time could be right after ...


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