## Nuke it from orbit.

It's the only way to be sure.

This might be a pretty boring answer, but if your obstacle is a city, and removing the city would give you success, then that problem is fairly easily solved. Bombing cities has been the best way to destroy cities for a long time now- why change the status quo?

Yes, yes I see 

> PS: No nuclear weapons. I have a severe allergy to nuclear detonations.

So **conventionally bomb it from orbit**. (A much less catchy and memetic headline though.)

We have [pretty big non-nuclear bombs][1]. And who says you have to just use one anyway?

Or not from orbit: drone bombers would probably be more effective anyway.

If you actually want the "orbit" part, or have something cooler than normal bombing- [just drop stuff on them from space][2]. It's called kinetic bombardement and I hear it's pretty deadly.

PS. Loudly playing The Bieber might have more effect than you give it credit for. There are such things called [sonic weapons][3], after all.


  [1]: http://www.popsci.com/military-aviation-amp-space/article/2009-08/pentagon-wants-deploy-largest-non-nuclear-bomb-next-year
  [2]: https://en.wikipedia.org/wiki/Kinetic_bombardment
  [3]: https://en.wikipedia.org/wiki/Sonic_weapon