In my world , top scientists genetically engineer a type of Wild Dog with intelligence on par with 8 year olds ( here is a scale of reference ) ,the bite strength of grey wolves, 2.5 inch canines, a high resistance to diseases such as rabies and canine distemper, and the ability to climb. These scientists release 5000 of these highly social animals into Detroit, where they separate into 5 super-packs.
After a while, a meeting is held between the packs, and it is decided that they will work together to make this city a home of their own, without a human presence. They then populate various abandoned buildings and stadiums and increase their population as quickly as possible, doubling their adult population each year. After this, they proceed to inhabit more and more abandoned buildings, until there are almost none left. While this is going on, they start to become more and more aggressive towards humans, killing and eating pets, and killing (and consuming) lone humans in the night. They continue their spiral into aggression until it is ten times more likely to be killed by a wild dog in the night than human.
As animal control gets increasingly involved, they change their game. They post lookouts around the city to monitor human activity, and report the locations bait traps are placed. The wild dogs even go as far as releasing rats into the homes and headquarters of those who attack them, causing widespread rat infestations and destroying their equipment, and targeting them and their family members when they are off work. After three years, they've created a well established surveillance network and increased their population from 5,000 to 30,000. They finally embark on their final task: depopulation. Due to their excellent team work, they turn the once great city of Detroit into a complete ghost town dominated by its new masters: Wild Dogs.
My question is: is there any way that canids could substantially decrease the population of a city in an economic and infrastructural state such as that of Detroit by decreasing the standard of living or manually eliminating the population?