A space colony that resembles the design of a Stanford torus generates artificial gravity by centripetal force.
Discussions about benefits of such fake gravity can be easily found: no more constant physical exercise like in today's space ships (you can concentrate on your mission); many activities that are not possible in today spaceships may be possible with artificial gravity.
Discussions about differences with real gravity can be found too: some say that if you throw up a coin, it won't describe the same curve as in Earth. Due to the rotational velocity of the torus, the coin will fall down and towards the direction opposite to the torus rotation.
If we cannot return to Earth:
How many generations are needed for any change to start to show? Of what might those changes consist?