Intuition on these scales can be tricky. In the simplest way of thinking, there's no limit, but a practical limit does arise.
We're used to motion where there's lots of friction. Because of that, we're used to the idea that a small force cannot move a large object. But really, if you have a small force on a large object, it just means the acceleration is really small. So as long as you have fuel, you can accelerate said moon. No laws of physics will get in your way.
Of course, you say "no shortcuts." You specified you meant no tricks like hyperspace or wormholes, but I'd like to point out that your ship has to have some propulsive device. How that device works will matter for these extreme problems. If you can just magically produce force by pushing on the universe or some pseudoscience phrasing like that, you may just have a really long trip ahead of you. However, if you're using any form of propulsion we have ever dreamed of, you'll be using a reactionary mechanism: you push exhaust out of the back of your ship really really fast, and that force has a reactionary force on the ship which moves it forward. This should feel natural -- its how quite literally every vehicle mankind has ever created works.
In space, we are dominated by the tyranny of the Rocket Equation. Long story short, we don't just get to accelerate our payload. We also have to accelerate all of the fuel needed for the rest of the trip. This fuel mass typically accounts for the vast majority of the mass of a rocket. As it works out, these effects lead to a natural limit measured in terms of delta-V. For any rocket, they can change their velocity by so many meters per second before they run out of fuel. It doesn't matter in what direction. For any practical science fiction involving rockets, this is a key metric to be aware of.
So how much can we accelerate a body like a moon? If you have a very large rocket, we'd have to do these complicated equations. But it sounds like you want a very small rocket, and for the case where the propellant makes up a very small fraction of the payload, we can handwave away all of the exciting exponentials of the real equations and just treat this like a normal physics problem. We apply a force to a moon over a period of time, and get a change in velocity out of it.
So let's grab numbers. Let's use a SpaceX Falcon Heavy to move our moon. The Falcon Heavy fires for 154.3 seconds with a max force of 16.2 MN. For simplicity, we'll assume it achieves that force for the entire flight. The moon is $0.07346\cdot10^{24}$ kg. Using F=ma, we see that the acceleration is about $2\cdot10^{-16} m/s^2$. Multiplied by the burn time, we get a change in velocity of $3.5\cdot10^{-14} m/s$.
Congratulations, you can get to Alpha Centauri in 10,000,000,000,000,000,000,000 years! Importantly, this is less time than it takes for the predicted heat death of the universe. However, Alpha Centauri-B having an expected life of only 20,000,000,000 more years, you may be rather disappointed when you arrive.
Well, almost. On these time and speed scales, there's more to account for. The above calculations assume space is empty. It is not. There's a fine haze of hydrogen atoms called the Interstellar Medium (ISM). There's not much mass out there, a mere trillion molecules per cubic meter. But over time it adds up. Our sun is traveling through its local part of the ISM at a rate of about 25km/s. We can assume other stars have similar rates. At 25km/s and the cross sectional area of the moon is [about]7 10,000,000 km^2, so a moon traveling at roughly the same velocity as our solar system would plow through 250,000,000 km^3 of ISM every second. That's on the order of 500,000kg/s of hydrogen. This imparts 12500MN of force. (assuming non-elastic collisions -- the actual math is more complicated, but wont change the story)
Remember, our Falcon Heavy only outputted 16.4MN. So if you were burning one Falcon Heavy in the middle of the ISM, you could barely overcome the drag forces applied to your moon. 154.3 seconds later, you're out of fuel.
So practically speaking, with a small rocket, you'll have to go where the winds take you.