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I'm writting a hard-science book where adult humans with the help of genetic engineering can undergo metamorphosis, could it be possible?

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    $\begingroup$ How is this different from your previous question? worldbuilding.stackexchange.com/q/233442/30492 $\endgroup$
    – L.Dutch
    Jul 31 at 18:41
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    $\begingroup$ By the way, reposting a question to circumvent a closure is not exactly appreciated $\endgroup$
    – L.Dutch
    Jul 31 at 18:43
  • $\begingroup$ I think you've misunderstood the term "hard science", and not just as applies to this site. $\endgroup$ Jul 31 at 19:15
  • $\begingroup$ If the reason you reposted is because you happened to have troubles finding your old question, know that you can look at all your posted questions on your profile... Here! Otherwise, if it's to improve your old question and get better answers, try to understand the issues of the old one (hopefully we were clear enough) and edit it :). $\endgroup$
    – Tortliena
    Jul 31 at 20:54
  • $\begingroup$ (a) If you read the mouse roll-over text for science-based and hard-science you will learn that they are mutually exclusive. (b) The hard-science tag refers to the nature of answers on this site. It has little to do with the "hard science" genre of Science Fiction other than it demands (and I mean that, demands) that answers prove themselves correct with mathematics and citations to credible journals, etc. As a rule, if you don't have the ability to judge the answer to a hard-science question, you should think long and hard about using the tag. It's ruthless. $\endgroup$
    – JBH
    Aug 1 at 0:23

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Absolutely!

Genetic engineering can effect the metamorphosis of sickly todders doomed to a short life of illness. They can be transformed into normal healthy people!

ashanti https://www.youtube.com/watch?v=IgES04-cSr8

https://www.ashclinicalnews.org/spotlight/feature-articles/gene-therapy-comeback-kid-hematology-treatments/

Ashanthi de Silva was the first human to be treated successfully with gene therapy. At the time, in 1990, she was a 4-year-old living with severe combined immunodeficiency (SCID), which is caused by insufficient levels of the enzyme adenosine deaminase (ADA). Without treatment, patients rarely survive toddlerhood. In addition to hematopoietic cell transplantation, standard treatment at that time consisted of lifelong replacement with synthetic ADA given via intramuscular injections once or twice weekly. However, few patients achieve full immune reconstitution and improvements in immune function can wane in just a few years with enzyme replacement therapy. Turning to a cutting-edge treatment, scientists were able to deliver to Ashanthi a healthy version of the gene that produces ADA using a viral vector. She is still alive today.

She is the first but now there are many others, with a wide range of illnesses. These inherited diseases are truly terrible. The afflicted and their families suffer and suffer. The prospect of a metamorphosis from a person with a genetic curse into a person without one is one of the most amazing metamorphoses I can imagine!

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