Let's say that Australia has been taken over by a hyper-aggressive fungus that grows on any biological life form larger than an ant. The stuff covers the entire continent, has subsumed every form of life on it, and is capable of a primitive form of photosynthesis in order to stay alive when other life runs out.
However, it can't expand outside of Australia, even if someone carved a sample of the stuff out, shipped it to another continent, and let it loose.
Why is this? What biological or chemical mechanism would stop a fungus from reproducing outside of that one landmass?
It evolved to not grow on ants because of the square-cube law; ants don't have much usable mass (volume) relative to the amount of fungus required to kill an ant and utilize its mass (surface area). Something like a human or an elephant has a much greater ratio of volume to surface area, meaning that the fungus gets more "bang for its buck".