I'm working on a story where cryogenic technology was made viable in the early 21st century (2026 or thereabouts) and became widespread due to an ageing elite seeking to put off their death, the private space industry using it to bypass issues with transporting untrained people through the expanse of space, the insurance industry as an option that people offered to people who don't necessarily understand what they are signing up for, and simply people with terminal illnesses trying hoping for a future cure.
Fast forward a century or so and there are millions of people in cryostasis, possibly hundreds of millions, often in poor physical condition with no one to pay for their resuscitation. What makes these people doubly unfortunate is that it was decided the most cost-efficient method of storing someone in cryostasis was to remove whatever is unnecessary to minimize their storage footprint. Thus, a large percentage of these people are rendered as little more than a head or simply a brain and ancillary bits (not sure if the spine would be preserved yet).
The end result is that those waking in the future are, due to a legal case, effectively indentured workers for whoever it was that resuscitated them. These people have rights; of course, those in charge are wise enough to know that nobody wants people with full prosthetic bodies staging a revolt. This is due to the fact that most people being resuscitated are fitted with rather strong and durable full-body prosthetic as hazardous work environments tend to have the highest demand.
This scenario is set some 200 or so years in the future.
Humanity has colonized the solar system through the use of an STL propulsion system derived from research into the Alcubierre drive. (Its gradually getting better)
Stations, moons, asteroids, and small rocks have been and are being colonized or mined.
Indentured workers have roughly equal rights as regular workers but with exceptions. They can leave the employ of those that resuscitated them, but only if someone else picks up their debt contract and in the worst-case situation they can go back into stasis. Shenanigans such as putting full-body prosthetic workers on less than subsistence living are cracked down on. It's not perfect, it's not pleasant, but that is the reality they woke to, and they have a second chance at life.
The full-body prosthetics vary to a fair degree in quality and build. At the shallow end would be Civilian, something like a Frame from Destiny but with a braincase in its abdomen, to simulacrum grade, which could be a Ghost in The Shell type full-body prosthetic.
The power players are a mix of planetary governments, state states, and megacorps with some smaller organizations operating in the background.
Thematically I was aiming for a setting between Cyberpunk/Shadowrun (sans fantasy elements) and The Expanse (sans protomolecule).
Edit 3: Removed original question for being too broad.
Edit: To clarify these people are effectively brains in a jar cyborg.
EDIT 2: (to specify the question further) Specifically, and most relevantly, I would be wondering about the person(s) well being with them awakening to their new existence as a 'brain in a jar' cyborg. Namely, what issues would arise psychologically and physically?
I don't necessarily need to know how such things would be addressed, but what they would be so that I may inquire into them through alternate means.