# Can super-powered poison resistance be tested on tissue samples?

If someone might have super-powered immunity to poison (ranging from you can't be poisoned by anything, to immunity to the bite of the North American cottonmouth, and you live in New Zealand), is it feasible for people to set up a system where they take tissue samples for testing?

Known poisons, so they would know what to look for. I was thinking it was more likely to work for hemotoxins than for neurotoxins or heavy metals -- they would find it useful to test for even a few that way.

Edit: This immunity is a full-blown superpower that means you are simply not affected by the poison, just as Superman is not affected by bullets. Unfortunately for the characters, they do not a full-blown superpower to detect what superpowers a person has, so they have to resort to realistic tests.

I was thinking on the order of adding some hemotoxin that destroys red blood cells to a sample of blood, slap it under the microscope, and diagnose based on whether the sample's cells are breaking down. And if so, what sorts of poisons have effects that can be practically tested with tissue samples.

• I was about to answer this off the cuff, but it bears some consideration. Most toxins are detoxified by liver cells. You can grow liver cells in culture. Could you test toxins against liver cells in culture? Maybe it has been done. I need to read more. If someone else reads and beats me to it, post your answer w links! – Willk May 14 '20 at 1:31
• you can't be poisoned by anything that's impossible - the dose makes the poison. E.g. won't be able to avoid CO2 poisoning "CO2 levels of more than 30% act rapidly leading to loss of consciousness in seconds." – Adrian Colomitchi May 14 '20 at 2:05
• @AdrianColomitchi: The OP specifies known poisons. This approach will clearly not work for all poisons; for example, lye. But could it work for specific poisons? – Willk May 14 '20 at 2:31