I already asked this on Medicine SE and Chemistry SE, but both said this question is dangerous and they can't answer it, and on Chemistry I got a suggestion to ask this here again.
It is for a RPG campaing. Are there any options that an evil person could use to keep someone awake against their will? Like a gas, an injection, or any substance or simple practice that wouldn't allow them to sleep even if they wanted to?
If any costs are involved, I would like to know the most cheap and viable ways to achieve this.
Furthermore, if there is a way for the victim to be be unaware of why they can't sleep, I would like to know that too.
The technology context is 80's decade, in real world and the purpose is a that a organization want to make some experiments about the consequences of sleep privation, especially if there is a point when allucinations begin.