In the future, baseline humans are joined by gene-hacked humans, cyborgs, uplifted animals, and digital consciousnesses (synthetic or uploaded minds). Most states are either autopias (automated utopias), digital realms (everyone lives in simulations), or hivemind (not Borg-style ones, most common are integrated direct democracies). AI and automation run almost everything and can do almost everything for (in the cases of autopias and digital realms) or with (in the case of hive minds) the humans. You can live in the many Dyson Swarms or on cold rocks in the void, but the superminds will know about you. Not everything, if you don't embrace dataism, but enough to manipulate and control you. Most people just join one of the superminds and live in or as them
How could a group of baselines live a life free of the superminds intervention?
Leaving and hiding are out, as you can't catch the colonization front and as it would be futile anyways.
Becoming a subject of a "friendly" supermind is out, as you wouldn't even realize that you are being spied upon.
Waging a war is out as it would force you to become like your enemies just to stand a chance.
Living as a nomad in space is out as it would just change which superminds are manipulating you on a regular basis (or not if they decide to keep you).