Apparently, Rocky Marciano (the model for Rocky Balboa) had a punch measured at approximately 1000ft-lbs, or 1355 joules in less weird units. He weighed a mere 85kg, so he's a bit lighter than your target 100kg, but it seems close enough.
Lets assume that all else being equal, the energy of a punch scales linearly with the weight of the puncher. A 100kg Rocky would generate 1600J in a punch, and your target is 12.5x that. Assuming you can model a punch using the good old $E_k = \frac{1}{2}mv^2$ equiation, to reach 20kJ he'd need to punch about 3.54x faster (because velocity scales in proportion to the square root of the kinetic energy). A fast human punch is about 15m/s (Ricky Hatton was clocked at 32mph, about 14.3m/s, and similar speeds have been observed in other boxers and karateka). Your super-punch therefore needs to be travelling a little over 53m/s. For reference, that's about 119mph.
A black powder musket, by the way, develops a muzzle velocity of over 120m/s, and a medieval crossbow would manage a little over 90m/s. A roman sling bullet on the other hand only managed 45m/s, and they're know to be pretty hazardous things.
So, your peeps can punch 3.5x faster than regular humans, delivering about 12.5x more energy. Force is defined as $F={\Delta p \over \Delta t}$, the change of linear momentum over time. Momentum, $p=mv$ is proportional to velocity. Lets assume that the time over which momentum is changed is the same for your peeps as it is for regular modern-day human boxers (which is a slightly dubious assumption, but it'll do), so the force of a super punch will be 3.5x stronger than for a regular human.
I found a few more sources for the force a boxer's punch than for the energy of the punch. From this short article, we get a punching force of 1300lbs, eg. 5783N. This mentions a 400kg punching force, eg. 3923N. This suggests that Wladimir Klitschko could develop 5000N of force. He's a bit heavier than your target weight at 109kg. but lets use him as our model.
Using these assumptions, your super-punches develop a force of 17.7kN, which is motor-vehicle-accident level. Exactly how this translates into damage effects though, is hard to say. As Adrian observed above, this amount of force will be extremely bad for the puncher, who risks destroying their own hand and arm unless they have the required secondary superpowers of having really tough bones and flesh. They'll need to work on punching technique to avoid pushing themselves away, or otherwise being unbalanced. A good uppercut would let them push against the ground (which hopefully isn't too soft!) and the energy involved will be enough to lift a 100kg victim off their feet and into the air, streetfighter-style.
Obviously, punching an armoured opponent in the chest would be a silly idea, because if they're decently protected (and a medieval knight certainly would be) you're not going to do much more than knock them over. They're clearly strong enough to lift an armoured knight off the gound and slam him into the ground, probably with enough force to kill if the surface is hard enough and certainly with sufficient force to give them some nasty concussion that will take them right out of the fight. Why risk your hands punching? Punching is a terrible way to fight, and only done by people who can't use weapons!
That said though, if all that force was concentrated on an area of just 1cm2 (say, a knuckle or two) you'd generate an impact pressure of 177MPa. That's quite a lot, and perilously close to the yield strengths of medieval steel. I can't be certain than your super-punchers could dent a breastplate just be punching it, but they're not far off. Even with the simplest of weapons (such as some simple spiked knuckles) they could probably breach armour.
As to the effect on unarmoured foes... well. A punch to the head will be fatal, more or less immediately, through traumatic brain injury and probably a fractured neck into the bargain. A punch to the chest could eaisly break bones, which may in turn cause a punctured lung (especially with a followup punch), an almost certainly fatal injury in medieval times or simple inability to breath due to flail chest. There are a whole load of other chest injuries, most of which are likely to be debilitating and later fatal in the absense of modern medical care. Blows to the abdomen will probably rupture internal organs. Blows to the liver or spleen will be immediately debilitating, and death can follow fairly swiftly from internal bleeding. There will be crush damage to overlying tissue, though under the circumstances this probably won't be a big concern to the victim.
Basically, it'll be like using a mace on an unarmoured target.
There's some more investigation to work out just how tough your super-punchers would have to be to withstand the forces of their own attacks, but they're likely to be formidable combatants. The most sensible thing of course would be for them to don armour and carry weapons, to increase their power and resilience yet further...