In a dystopian future, genetic editing, stem cell research and cloning have become commonplace. Humans in embryo can be genetically modified and designed to a immense variation; some people can give themselves scorpion tails, for example, while others make their brains twice the size. Professional swimmers have fins and webbed digits, professional bodybuilders have inhuman muscle mass etc...
Human anatomy can be redesigned to whatever shape a scientist can imagine.
Due to cultural collapse, there are no legal or moral restrictions on the extent of genetic editing.
A mega corporation wants to exploit this. This corporation presently hires millions of office workers, fulfilling a multitude of admin and secretarial duties. They consider regular humans to be inefficient and cost ineffective. The corporation wants to lay off all their current admin workers, and replace them with an army of cloned super secretaries.
So, what modifications should be made to the typical human design in order to make these office workers more efficient?
Answers might include additional arms to help them type faster, or modified brains so that they will not be distracted by any social activities, or even crippled legs so they can never leave their desks. The admin jobs in question are all low paying, require limited creativity, and are based solely around using computers.
For legal reasons, these factory farmed workers are not 'human', and no human rights apply.
The corporation cares solely about reducing cost and streamlining efficiency. They want to design a template for the ultimate office drone, to be reused across their business.
Anything biologically feasible is possible, with some flexibility considering they're using future tech.