Would it be possible to realistically invent a substance that causes insomnia? What would be the uses and consequences of such a substance?
closed as off-topic by bowlturner, Serban Tanasa, grimmsdottir, Vincent, Ghanima Mar 28 '15 at 15:05
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Yes - anything that inhibits melatonin. A more detailed explanation can be found at this link
The major cause of insomnia is the failure of the body to produce sufficient amounts of the neurotransmitter melatonin. This chemical induces us to sleep in conditions of total darkness.
Thus, theoretically, if you could find something that inhibits the production of melatonin or causes serotonin deficiency, then that should cause insomnia.
Edit: There is a list of drugs that cause insomnia at the end of the link given, but they would have other side-effects and may cause insomnia due to other reasons.