For a cultural anthropological precedent, consider the indigenous peoples of Australia.
They lasted upwards of 50,000 years in almost complete quarantine.
Could you imagine catching that much in one day using only a spear?
And then again the next day and the day after that? I said it would be
just about impossible. Aboriginal people, she said, have been doing it
every day for at least 50,000 years.
For 49,800 of those years they had the continent to themselves. There
were once about 250 distinct Aboriginal languages, hundreds more
dialects, and many more clans and subgroups. But there is deep
spiritual and cultural overlap among them, and indigenous Australians
I spoke with said it was not insulting to combine everyone together
under the general title of Aboriginal. They call themselves
Aboriginals. They lived for a couple of thousand generations in small,
nomadic bands, as befits a hunter-gatherer existence, moving in their
own rhythms about the vast expanse of Australia.
But you might want to consider the outcome.
Then on April 29, 1770, British explorer James Cook landed his ship,
the Endeavour, on the southeastern shore. The next two centuries were
a horror show of cultural obliteration—massacres, disease, alcoholism,
forced integration, surrender.
From First Australians
What you are asking, in effect, is 'How did the original wanderers, 50,000 years ago, who happened upon this new land, but ended up stranded here with no way back, feel about their prospects of returning to where they came from? And what was their response when they faced the inevitable?'