He will not have time to notice any biological differences...
...because he is made of antimatter, and will instantly annihilate on contact with any normal matter nearby.
The maneuver you're describing--picking someone "hyper-up" and flipping them around--is exactly the operation that a non-orientable wormhole ( https://en.wikipedia.org/wiki/Non-orientable_wormhole ) would do to matter that passes through it. This would affect the chirality of the molecules that pass through it, yes, but it also does something at a deeper level:
As well as turning left-handed screwthreads into right-handed
screwthreads, and left-handed gloves into right-handed gloves,
reversing the chirality of an object is also usually associated with
the idea of reversing the sign of electromagnetic charge – if a
positron can be considered as a time-reversed electron, it can also be
considered as an electron aging conventionally, but with one spatial
dimension reversed. The existence of a traversable nonorientable
wormhole would seem to allow the conversion of matter to antimatter,
and vice versa.
In conclusion, J. Random would go out in a blaze of total-energy-conversion glory and take a sizable check of the earth's crust with him. 
[Edit: I just noticed that @Spencer and @Eth already pointed this out long ago in the comments, including a reference to the oon-orientable wormhole article. I feel properly scooped, but I'll leave my answer up since no other actual answers address this...]