My current ongoing science fiction project has FTL travel that is instantaneous for the ships and their crews, but still, usually, takes years of real-time in the rest of the universe. This is going to have an effect on crews as they are going to lose every contact they make off-ship with every jump they make. I've already assumed that ships crews will be separated from the rest of society; partly by a certain mystique but also by an isolationism that cuts both ways.
Crews on established circuit routes will usually take 20-30 years to complete a circuit back to a given port, often stopping for only a few weeks at most. Even the people who are still alive will not be the same people they left behind. Crews don't want to get attached to someone they'll likely never see again and people know they're unlikely to ever meet the same crewman twice. So crews will have minimal contact with the outside world, but I'm wondering what the long-term effects of repeatedly losing the few contacts they do make in port might be.
In particular: Would the symptoms from the repeated loss of all of a person's contacts outside their workplace simulate them aging prematurely, psychologically and/or physically?
Answers will need to be grounded in the known science of relationship loss and the long-term effects of repeated trauma and grief. The society is generally much like our own, which means that you're just as likely to find drug abuse, bigotry, and violence in a given population as we might expect to see today. The one other factor that may be important to note is that, apart from the ships themselves carrying message traffic, there are no FTL communications in this universe.