If you mean actually replacing their skin with Chrome, and excepting it to work, it just won't. Firstly lets look at the functions of skin and what Chrome can do when its replaced.
Firstly the skin has two layers. A dead layer, which is what you would usually consider skin which is usually just a bunch of dead skin cells and a living layer with blood vessels, nerves, oil and sweat glands and hair follicles. If you want to replace your skin, your going to need to replace both. Otherwise, your going to grow a layer of dead skin underneath your chrome skin and thats going to make it extremely uncomfortable for you since your going to feel all that dead skin itching to get off you.
So your going to need to replace the living layer layer with chrome and your going to need to replicate all its functions. Thats okay, we have super advance technology and computer systems. I guess you could replicate most of it.
First one, is protection. Your skin protects you from the outside world. Chrome will do roughly the same thing. Physical, fluids, radiation and infections. It should stop those. Its also fairly nonreactive as a metal so you should be fine with it being exposed to the air for a long time. If you get a scratch or it gets damaged, you just visit the doctor and get it patched up. You also pray to god that the wound is small so it can clot and your body can protect itself and you don't get an infection on your way to the doctor. So lets just give that a tick.
Second is Thermal Regulation. Our skin is how we regulate temperature. Sweat and blood vessels run through it so we will need to be able to duplicate that functionality with chrome. Micro sized holes in the chrome would work, but we have replaced the living layer of skin that we had, so none of that is there. Just a layer of protective fat. Your going to have to create some super small artificial sweat glands and an impossibly delicate network of artificial veins to be able to regulate your temperature. So we can do that with our future tech. Now here is the issue. Chrome (atleast when I googled it) seems to be a decent conductor of heat like steel. Do you know what happens to metals left in the sun on a nice sunny day. They heat up to crazy temperatures. Doesn't matter if your nice silver and shiny, your going to be absorbing heat. If you stay out in the sun too long, your going to cook yourself alive, which will be a nice and pleasant experience. The next problem is in the rain and snow. The cold is going to go straight into your internals and its going to send you into shock after a couple of seconds. So I guess as long as your never in direct sunlight, and never in direct contact with rain, water, ice or snow your going to be okay. So lets give that a big fat yes.
Next is sensation. Your going to want a sense of touch and you've replaced all your skin. No problem. There are tons of different sensors that can replicate touch. You would have a fine and delicate network of piezoelectric materials embedded into your skin. When you touch something, the materials will stretch due to friction and you transmit that into nerve signals with some fancy electronics and tadaaa you have a sense of touch. That couple with a variety of other sensors, like temperature, electrical and maybe some chemical ones, your going to have a even better version of skin.
Finally, our skin makes vitamin D for us and you've replaced it. No problems there, we just take a bunch of supplements as required, or maybe have a special drip feed system so you don't need to worry about it.
Now come some more mechanical aspects. How do you get flexible chrome skin? The answer is easy, lots of overlapping plates. Of course, this means bad stuff can get it as mentioned in the first function of skin. Still pretty easy, we have small artificial oil glands, that deposit minute amount of lubricant around these overlapping plates. That way we can be flexible and stay protected. You don't really want to touch though, since your going to be leaving lube everywhere now, but its only a small amount and skin leaves oil around as well so its all fine.
So there you have it. As long as the metal plating used is none conductive you can be a living and breathing metal person. Just make sure to avoid direct exposure to sun, rain and snow or your going to fry yourself or send yourself into hypothermia. Make sure you don't do anything risky either. Small cuts might be fine, but any larger, and your going to get infected pretty quickly. That or you can carry around a portable doctor to quickly neutralize and patch any wounds you receive. Don't forget your vitamin D either. Now that you can no longer generate it naturally, your going to need to keep a constant supply with you, but make sure you don't take it all at once or you risk overdosing.
Finally, make sure to check in with your advance team of highly paid, electricians, technicians, mechanics and doctors every couple of hours so that any damages, malfunctions and issues that pop up an be quickly replaced before you die.
Also... have fun trying to hold anything with your new and crazy smooth skin.