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Its a bit out of scope for this question because the creature would have to be small, but just after firing the main gun, the next action the crew takes is to open the breach and reload a round. With the breach open, there is a direct route from the tip of the main gun barrel to the inside of the crew compartment. An intelligent snake like creature with a diameter of less than 120mm could theoretically crawl right up the barrel and into the crew compartment while the crew was reloading. It would need to have tough skin though because it may suffer burns crawling through the barrel.

Most animals become injured when they are punctured by a bullet because it ruptures blood vessels and destroys organs that there may only be one or two of. But creatures with different anatomy may suffer far less damage. For example a sea sponge has no internal organs and is essentially homogeneous in construction. You can't really kill it by putting holes in it. A creature that didn't have a pressurized circulatory system wouldn't bleed out. A tree for example is able to live and regenerate even if its cut down to the stump in many cases.

Most military hardware includes nuclear event detectors that will shut down the electronics to protect them from the EMP associated with a nuclear blast. If a small burst of radiation were aimed at the tank the electronics would turn off until the crew manually reset everything. And of course it would be pitch black in there so it could take them a while. Those detectors are usually built into much of the essential hardware and cannot be disabled by the crew. The only way they could be disabled would be to send the components back to the defense contractors who built them and have them modified.

The M1A2 is coated with a Chemical Resistant Agent Coating (CARC). If the creature were emit a strong acid that could dissolve both the CARC and steel then it could easily make a hole in the armor. Alternatively, the CARC can be scratched off pretty easily, so if you can scratch enough off you can dissolve the steel with acid that way. Think of the movie Aliens.

There is no air conditioning in the M1A2. If you were to heat it from the outside the crew would be forced to come out. But the tank has a lot of thermal mass so that could take a while.

You can stop the M1A2 by killing the crew. You can kill the crew if you can pry open the hatch. Pulling on the hatches until the locking pins break is much easier than piercing the armor, but still may require a few thousand pounds of force.

The M1A2 uses a jet turbine motor. By its very nature the exhaust port can't be heavily armored. There is a covering over the exhaust, but its not as strong as the rest of the armor.

In order for the tank to function the crew needs to see. The M1A2 typically includes optics with infrared and night vision. These are the primary means by which the crew can tell what is going on. If the optics were disabled the crew would be forced to use the manual port holes. Those port holes have much more limited visibility than the cameras. Due to the limited visibility they may be tempted to open the hatch to get a better view (at least until they learned better).

The infrared camera only works if the creature is emitting some heat. So cold blooded would be helpful.

All of the cameras have exposed lenses. If the lens were to break the camera wouldn't work. The lens could be smashed, dissolved, or covered with some opaque substance spit out by the creature.

If the creature emitted some sort of mist they would be unable to see or target it effectively. The tank itself has smoke grenade launchers for that very purpose.

The tank has various antennas that stick out for radio and GPS. If they were pulled off the tank would be unable to call for help.

Another way to get the crew to exit would be to emit a strong horrible sound through the armor. Once they opened the hatch the hunt is over.

The main 60mm gun on the M1A2 is very powerful but has a low reload speed because a crew member has to manually change each bullet. That could take around 6 seconds between shots. If they miss the first shot that gives the creature plenty of time to get close without worrying about the main gun. The turret has a 50 cal machine gun mounted next to the main gun on the turret so the creature would still have to avoid that while covering the distance.

Most military hardware includes nuclear event detectors that will shut down the electronics to protect them from the EMP associated with a nuclear blast. If a small burst of radiation were aimed at the tank the electronics would turn off until the crew manually reset everything. And of course it would be pitch black in there so it could take them a while. Those detectors are usually built into much of the essential hardware and cannot be disabled by the crew. The only way they could be disabled would be to send the components back to the defense contractors who built them and have them modified.

The M1A2 is coated with a Chemical Resistant Agent Coating (CARC). If the creature were emit a strong acid that could dissolve both the CARC and steel then it could easily make a hole in the armor. Alternatively, the CARC can be scratched off pretty easily, so if you can scratch enough off you can dissolve the steel with acid that way. Think of the movie Aliens.

There is no air conditioning in the M1A2. If you were to heat it from the outside the crew would be forced to come out. But the tank has a lot of thermal mass so that could take a while.

You can stop the M1A2 by killing the crew. You can kill the crew if you can pry open the hatch. Pulling on the hatches until the locking pins break is much easier than piercing the armor, but still may require a few thousand pounds of force.

The M1A2 uses a jet turbine motor. By its very nature the exhaust port can't be heavily armored. There is a covering over the exhaust, but its not as strong as the rest of the armor.

In order for the tank to function the crew needs to see. The M1A2 typically includes optics with infrared and night vision. These are the primary means by which the crew can tell what is going on. If the optics were disabled the crew would be forced to use the manual port holes. Those port holes have much more limited visibility than the cameras. Due to the limited visibility they may be tempted to open the hatch to get a better view (at least until they learned better).

The infrared camera only works if the creature is emitting some heat. So cold blooded would be helpful.

All of the cameras have exposed lenses. If the lens were to break the camera wouldn't work. The lens could be smashed, dissolved, or covered with some opaque substance spit out by the creature.

If the creature emitted some sort of mist they would be unable to see or target it effectively. The tank itself has smoke grenade launchers for that very purpose.

The tank has various antennas that stick out for radio and GPS. If they were pulled off the tank would be unable to call for help.

Another way to get the crew to exit would be to emit a strong horrible sound through the armor. Once they opened the hatch the hunt is over.

The main 120mm gun on the M1A2 is very powerful but has a low reload speed because a crew member has to manually change each bullet. That could take around 6 seconds between shots. If they miss the first shot that gives the creature plenty of time to get close without worrying about the main gun. The turret has a 50 cal machine gun mounted next to the main gun on the turret so the creature would still have to avoid that while covering the distance.

Most military hardware includes nuclear event detectors that will shut down the electronics to protect them from the EMP associated with a nuclear blast. If a small burst of radiation were aimed at the tank the electronics would turn off until the crew manually reset everything. And of course it would be pitch black in there so it could take them a while. Those detectors are usually built into much of the essential hardware and cannot be disabled by the crew. The only way they could be disabled would be to send the components back to the defense contractors who built them and have them modified.

The M1A2 is coated with a Chemical Resistant Agent Coating (CARC). If the creature were emit a strong acid that could dissolve both the CARC and steel then it could easily make a hole in the armor. Alternatively, the CARC can be scratched off pretty easily, so if you can scratch enough off you can dissolve the steel with acid that way. Think of the movie Aliens.

There is no air conditioning in the M1A2. If you were to heat it from the outside the crew would be forced to come out. But the tank has a lot of thermal mass so that could take a while.

You can stop the M1A2 by killing the crew. You can kill the crew if you can pry open the hatch. Pulling on the hatches until the locking pins break is much easier than piercing the armor, but still may require a few thousand pounds of force.

The M1A2 uses a jet turbine motor. By its very nature the exhaust port can't be heavily armored. There is a covering over the exhaust, but its not as strong as the rest of the armor.

In order for the tank to function the crew needs to see. The M1A2 typically includes optics with infrared and night vision. These are the primary means by which the crew can tell what is going on. If the optics were disabled the crew would be forced to use the manual port holes. Those port holes have much more limited visibility than the cameras. Due to the limited visibility they may be tempted to open the hatch to get a better view (at least until they learned better).

The infrared camera only works if the creature is emitting some heat. So cold blooded would be helpful.

All of the cameras have exposed lenses. If the lens were to break the camera wouldn't work. The lens could be smashed, dissolved, or covered with some opaque substance spit out by the creature.

If the creature emitted some sort of mist they would be unable to see or target it effectively. The tank itself has smoke grenade launchers for that very purpose.

The tank has various antennas that stick out for radio and GPS. If they were pulled off the tank would be unable to call for help.

Another way to get the crew to exit would be to emit a strong horrible sound through the armor. Once they opened the hatch the hunt is over.

Most military hardware includes nuclear event detectors that will shut down the electronics to protect them from the EMP associated with a nuclear blast. If a small burst of radiation were aimed at the tank the electronics would turn off until the crew manually reset everything. And of course it would be pitch black in there so it could take them a while. Those detectors are usually built into much of the essential hardware and cannot be disabled by the crew. The only way they could be disabled would be to send the components back to the defense contractors who built them and have them modified.

The M1A2 is coated with a Chemical Resistant Agent Coating (CARC). If the creature were emit a strong acid that could dissolve both the CARC and steel then it could easily make a hole in the armor. Alternatively, the CARC can be scratched off pretty easily, so if you can scratch enough off you can dissolve the steel with acid that way. Think of the movie Aliens.

There is no air conditioning in the M1A2. If you were to heat it from the outside the crew would be forced to come out. But the tank has a lot of thermal mass so that could take a while.

You can stop the M1A2 by killing the crew. You can kill the crew if you can pry open the hatch. Pulling on the hatches until the locking pins break is much easier than piercing the armor, but still may require a few thousand pounds of force.

The M1A2 uses a jet turbine motor. By its very nature the exhaust port can't be heavily armored. There is a covering over the exhaust, but its not as strong as the rest of the armor.

In order for the tank to function the crew needs to see. The M1A2 typically includes optics with infrared and night vision. These are the primary means by which the crew can tell what is going on. If the optics were disabled the crew would be forced to use the manual port holes. Those port holes have much more limited visibility than the cameras. Due to the limited visibility they may be tempted to open the hatch to get a better view (at least until they learned better).

The infrared camera only works if the creature is emitting some heat. So cold blooded would be helpful.

All of the cameras have exposed lenses. If the lens were to break the camera wouldn't work. The lens could be smashed, dissolved, or covered with some opaque substance spit out by the creature.

If the creature emitted some sort of mist they would be unable to see or target it effectively. The tank itself has smoke grenade launchers for that very purpose.

The tank has various antennas that stick out for radio and GPS. If they were pulled off the tank would be unable to call for help.

Another way to get the crew to exit would be to emit a strong horrible sound through the armor. Once they opened the hatch the hunt is over.

The main 60mm gun on the M1A2 is very powerful but has a low reload speed because a crew member has to manually change each bullet. That could take around 6 seconds between shots. If they miss the first shot that gives the creature plenty of time to get close without worrying about the main gun. The turret has a 50 cal machine gun mounted next to the main gun on the turret so the creature would still have to avoid that while covering the distance.