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Possibly a LENR reaction would be compatible with biological processes that we are familiar with. Though widely considered impossible, enough scientists still think that LENR actually exists and is able to generate lots of energy that it would seem reasonable for a Worldbuilding scenario.

LENR reactions do not require extreme pressure or temperature and do not have the large radioactive byproducts that are so harmful for life. If LENR is real and the nanotechnology of biological processes could harvest the energy, it would seem a viable basis for a lifeform.

There is a chemical poisoning problem associate with LENR materials since palladium, nickel, etc. are used. But, perhaps a LENR reaction could be based on a suitably engineered carbon molecule. This seems like the best choice for a direct usage of nuclear power by a lifeform that I can think of.

To avoid life damaging radiation hazards you need something that either avoids the radiation in the first place - perhaps aneutronic fusion or such-like, or you must have a very powerful system of resisting and/or repairing radiation damage. Aneutronic fusion is unfortunately even more challenging than the mainstream fusion approaches. Any form of fission is loaded with ionizing radiation.

If an organism could somehow harness Pu-238 or similar isotope in the manner of a radioisotope thermoelectric generator (RTG) perhaps it use this as an energy source. Pu-238 is an alpha emitter and is quite harmful, Sr-90 is a beta emitter, but still ionizing. The RTG is a very simply nuclear design, but the radiation is still a very real problem. The simplicity of an RTG is a major plus if you could justify dealing with the radiation and the ability to renew your supply of your radioactive isotope of choice. All RTG isotopes are necessarily short half-life and not present in significant quantity in nature.

Then again, just how big can your lifeform be? If it is the size of a planet, good old uranium, thorium and potassium can generate plenty of heat and the levels are radiation are not very high -- just on that scale, the overall rate of heat loss is quite low.

Possibly a LENR reaction would be compatible with biological processes that we are familiar with. Though widely considered impossible, enough scientists still think that LENR actually exists and is able to generate lots of energy that it would seem reasonable for a Worldbuilding scenario.

LENR reactions do not require extreme pressure or temperature and do not have the large radioactive byproducts that are so harmful for life. If LENR is real and the nanotechnology of biological processes could harvest the energy, it would seem a viable basis for a lifeform.

Possibly a LENR reaction would be compatible with biological processes that we are familiar with. Though widely considered impossible, enough scientists still think that LENR actually exists and is able to generate lots of energy that it would seem reasonable for a Worldbuilding scenario.

LENR reactions do not require extreme pressure or temperature and do not have the large radioactive byproducts that are so harmful for life. If LENR is real and the nanotechnology of biological processes could harvest the energy, it would seem a viable basis for a lifeform.

There is a chemical poisoning problem associate with LENR materials since palladium, nickel, etc. are used. But, perhaps a LENR reaction could be based on a suitably engineered carbon molecule. This seems like the best choice for a direct usage of nuclear power by a lifeform that I can think of.

To avoid life damaging radiation hazards you need something that either avoids the radiation in the first place - perhaps aneutronic fusion or such-like, or you must have a very powerful system of resisting and/or repairing radiation damage. Aneutronic fusion is unfortunately even more challenging than the mainstream fusion approaches. Any form of fission is loaded with ionizing radiation.

If an organism could somehow harness Pu-238 or similar isotope in the manner of a radioisotope thermoelectric generator (RTG) perhaps it use this as an energy source. Pu-238 is an alpha emitter and is quite harmful, Sr-90 is a beta emitter, but still ionizing. The RTG is a very simply nuclear design, but the radiation is still a very real problem. The simplicity of an RTG is a major plus if you could justify dealing with the radiation and the ability to renew your supply of your radioactive isotope of choice. All RTG isotopes are necessarily short half-life and not present in significant quantity in nature.

Then again, just how big can your lifeform be? If it is the size of a planet, good old uranium, thorium and potassium can generate plenty of heat and the levels are radiation are not very high -- just on that scale, the overall rate of heat loss is quite low.

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Possibly a LENR reaction would be compatible with biological processes that we are familiar with. Though widely considered impossible, enough scientists still think that LENR actually exists and is able to generate lots of energy that it would seem reasonable for a Worldbuilding scenario.

LENR reactions do not require extreme pressure or temperature and do not have the large radioactive byproducts that are so harmful for life. If LENR is real and the nanotechnology of biological processes could harvest the energy, it would seem a viable basis for a lifeform.