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Jun 20 at 17:45 comment added Russell McMahon This and Vesper's answer are the MINIMUM period. If you have complete ability to examine and modify your genome , as may be the case, then a few generations to see what happens MAY be enough. If your genetic manipulation capabilities are similar to what we have now then 10 generations of careful watching MAY be enough.
Jun 19 at 15:44 history answered o.m. CC BY-SA 4.0