Most likely not

To simplify smell, a creature is taking in atoms or molecules into a sensor, and those atoms or molecules stimulate the sensor.

Searching the web it seems it's generally accepted that there are approximately 100,000 - 1,000,000 atoms per cubic meter. Contrast this with Earth's atmosphere at sea level, which has about 300,000,000,000,000,000,000 atoms per cubic meter (3*10^22).

Which means for every 1 atom in space you'll find 60 quadrillion atoms here on Earth. Your animals' senses of smell would have to be extraordinarily more powerful than any Earth creature.

Most likely not

To simplify smell, a creature is taking in atoms or molecules into a sensor, and those atoms or molecules stimulate the sensor.

Searching the web it seems it's generally accepted that there are approximately 100,000 - 1,000,000 atoms per cubic meter in Space. Contrast this with Earth's atmosphere at sea level, which has about 300,000,000,000,000,000,000 atoms per cubic meter (3*10^22).

Which means for every 1 atom in space you'll find 60 quadrillion atoms here on Earth. Your animals' senses of smell would have to be extraordinarily more powerful than any Earth creature's.