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Jun 5, 2018 at 0:10 comment added Perkins The single-path version would have the advantage (for some purposes) that once you'd taken a dose you'd have to continue taking it until you had some other method for getting rid of the E, thereby potentially allowing it to be used for ensuring loyalty.
May 28, 2018 at 15:03 comment added Erik Most people are opposed to swallowing large doses of P already.
May 28, 2018 at 7:10 comment added cmaster - reinstate monica @Brilliand That's another reason why I prefer the two-path. However, the one path can still work "correctly": The reservoir of A is depleted, so if the synthesis of A in the body is slow enough and the excretion of P fast enough, only very little E would be produced, which could well be below the threshold for lethality. It might still have some bad consequences, though, making people reluctant of swallowing large doses of P...
May 28, 2018 at 6:44 comment added Brilliand The one-path reaction sounds like it would become lethal later on, when you body has eliminated most of the P but still has a little bit left. You would have to constantly keep your P levels high to ensure that it doesn't decrease to a lethal dose.
May 27, 2018 at 21:52 history answered cmaster - reinstate monica CC BY-SA 4.0