This is a difficult question to ask since so potentially politically charged discussions and I'm making some large sweeping statements in trends. I am not saying anything specifically about whether I agree or disagree with any of the below, only the trends I believe I see. I ask that we avoid discussing the right or wrong of any of the below, or to what extent any applies currently, and focus only on the result of larger trends.
Prejudice against groups or factions have been around for all of human history. Some minority groups have gotten a particularly negative view and accusation of causing social ills throughout history, Christians, Jews, Irish, Hispanics, Homosexuals, and Muslims have all had the 'joy' of this distinction at one time or another.
In recent years we have made 'progress'. Racism was traditionally the most common prejudice, but recently science/genetics have led to some arguing that race is a construct with little justification; meanwhile the continued intermingling of races, partially due to such rapid transportation, have lead to racial lines growing increasingly intermingled making 'race' harder to define.
To a similar extent villainizing a nation, the way that happened during WW2 or during the Cold War, can become harder. Ease of communication with people from other cultures makes it apparent when stereotypes are unwarranted, and the rapid spread of cultural memes due to communication, travel & internet mean that increasingly shared culture is existing amongst geographically distant nations.
Finally, the internet allows people from minority ideologies or lifestyles to find each other and rally together to defend themselves against negative representations of their lifestyle, which I think is part of the reason cause like gay marriage were accepted so rapidly compared to similar causes of the past like bi-racial marriage.
The point being technology seems to have lead to trends that are causing traditional boundaries for prejudice to be less accepted with each generation. However, while I'm optimistic about this, the fact is human nature doesn't change; and we're evolutionarily predisposed to creating "us vs them" groups that make it easier to justify mistreatment of the "them" group.
So, if we accept my premise that the traditional boundaries mentioned above will continue to grow less acceptable, but that humans will still find ways to be prejudiced, then the question is where will that prejudice appear? Will there be a new class of "acceptable targets", or some new form of ideological division between "us" and "them" that are deemed acceptable for justifying treating a member of the group worse in the near future even as science is working hard to disprove baseless accusations and fast communication makes rumor mongering easily disproved?
I'm looking at near-future, say a generation or two, and particularly want to look at how the technology is helping to modify culture, presuming fast instantaneous communication and internet is now ubiquitous.